基于微流控的人卵母细胞特性检测

人的卵母细胞特性的研究对于临床医学具有重要意义,可以通过卵母细胞的大小对其活性进行研究。采用微流控平台与MATLAB算法相结合的方法,利用微流控器件的沟道对卵母细胞进行挤压,由于卵母细胞的活性不同对于挤压的反应也不同,活性越好的卵母细胞通过沟道时变形性越好,经检测卵母细胞有很好的活性;拍摄卵母细胞发生形变与卵母细胞通过沟道的视频,利用MATLAB程序进行图像处理得到卵母细胞的大小,测得卵母细胞的直径约为170μm。这种方法有别于传统方法,在一定程度上使用了算法识别,提高了卵母细胞分析统计的准确度,提升了工作效率。由于人的卵母细胞比较珍贵,只进行了初期实验研究,证明此方法确实可行。     

EmotionMap: Visual Analysis of Video Emotional Content on a Map

Journal of Computer Science and Technology - Emotion plays a crucial role in gratifying users’ needs during their experience of movies and TV series, and may be underutilized as a framework...     

数据信息化时代下的工程造价管理

在经济不断迅猛发展的形势下,新时代的经济形式催生出一些多元化企业和职业,信息技术的不断发展使数据信息成为最具价值的财富。在信息传播极其迅速的今天,工程造价在数据信息时代下的管理模式也不断更新变化,以适应多元化的工程项目形式。因此信息数据的大量搜集和相关研究受到了各大科研机构和各类企业的高度关注。     

铸造式和焊接式主轴箱体的动态特性对比分析

利用有限元法和试验模态法对立式加工中心的铸造式和焊接式两种结构的主轴箱体进行了模态分析,分别获得了其前六阶固有频率和振型。通过对比两种方法获得的结果,验证了有限元分析模型的有效性。研究表明,两种主轴箱体的阻尼比接近,但焊接式主轴箱体的各阶固有频率均要高于铸造式主轴箱体的各阶固有频率。并且铸造式主轴箱体的固有频率更接近于机床主轴的常用工作频率,焊接式主轴箱体的则远离此频率。因此对于常用主轴转速而言,焊接式主轴箱体的动态性能要优于铸造式主轴箱体的动态性能。     

一种快速解压的无损压缩算法

随着信息技术的不断发展,大量数据给存储和传输都带来了巨大的挑战。数据压缩能够有效减少数据量,方便数据的处理和传输。无损压缩是一种利用数据的冗余特点进行压缩的压缩方法,解压时可以完全还原数据而不会有任何失真。在研究LZO算法的快速解压原理基础上,设计了一种新的压缩算法。该算法通过减少压缩数据中压缩块的数量,降低了解压程序的执行开销。测试结果表明,新算法可实现比LZO算法更快的解压速度。     

Inter-diffusion Based Analytical Model for Growth Kinetics of IMC Layers at Roll Bonded Cu/Al Interface During Annealing Process

Metals and Materials International - A model based on inter-diffusion theory was established to predict growth kinetics of the intermetallic compounds (IMCs) formed in roll bonded Al/Cu sheets...     

Optimization of C/TiCx duplex diffusion barrier coatings for SiCf/Ti composites based on interfacial structure evolution exploration

Introducing a carbon single coating is a popular method used to protect SiC_f/Ti composites from severe interface reactions. However, carbon coatings lose their protective effect on SiC fibres at high temperature, even after a short period time. As such, given the strong demand for high temperature applications in aeronautics and astronautics a more coating which is more effective at high temperatures is desirable. In order to improve the high temperature interfacial stability of SiC_f/Ti composites, a C/TiC_x duplex coating system with different C contents in TiC_x was introduced to explore the protection of fibres at 1200?°C for 1?h. The results show that the C/quasi-stoichiometric TiC coating system protects the SiC fibres most effectively. Based on insights from the evolution of the interface structure, TiC_x has been identified as an interfacial reaction product from the C single coating, exhibiting a gradient in C content and grain size, which is different from a deposited TiC layer with a well-distributed composition and structure. The different coating structure gives rise to different ability to resist C diffusion at high temperatures, in which poor resistance ability appears in TiC_x interfacial reaction layer coming from C single coating due to short-circuit diffusion in C-rich fine-grained TiC layer and fast intracrystalline diffusion trigged by amounts of vacancies in sub-stoichiometric coarse-grained TiC layer. Therefore, C/quasi-stoichiometric TiC duplex coatings with a thick, coarse-grained quasi-stoichiometric TiC layer could effectively inhibit C diffusion by comparison to C single coatings, and is more effective than C/rich-carbon TiC duplex coatings due to the existence of short-circuit diffusion in the latter. As such, C/quasi-stoichiometric TiC duplex coatings appear to be an optimal diffusion barrier for SiC_f/Ti composites at high temperature.     

基于微型塌落筒和稠度漏斗的膏体充填料浆流变参数预测研究

充填料浆流变参数的准确测定是合理评价其管道输送特性的关键，目前充填料浆流变参数主要采用流变仪测试，工程适用性较差。基于圆锥塌落筒模型和圆柱塌落筒模型，结合流变仪测试，对比分析了不同形状尺寸塌落筒测试屈服应力的准确性，确定了微型塌落筒最佳形状尺寸为柱形 100 mm×100 mm；在此基础上构建了屈服应力-塌落度关系模型，经验证在无量纲屈服应力范围为 0~0.1 时该模型可以准确计算料浆屈服应力；通过自制稠度漏斗测试充填料浆流出时间，探索流变仪测试塑性粘度与流出时间关系，结果表明相同质量浓度时，料浆流出时间与其塑性粘度呈负相关关系，料浆质量浓度变化时其流出时间与塑性粘度关系不明显。     

D-limonene Inhibits Pentylenetetrazole-Induced Seizure via Adenosine A2A Receptor Modulation on GABAergic Neuronal Activity

Background: Epilepsy is a chronic neurological disorder characterized by the recurrence of seizures. One-third of patients with epilepsy may not respond to antiseizure drugs. Purpose: We aimed to examine whether D-limonene, a cyclic monoterpene, exhibited any antiseizure activity in the pentylenetetrazole (PTZ)-induced kindling mouse model and in vitro. Methods: PTZ kindling mouse model was established by administering PTZ (30 mg/kg) intraperitoneally to mice once every 48 h. We performed immunoblot blots, immunohistochemistry (IHC), and high-performance liquid chromatography (HPLC) analysis after the behavioral study. Results: An acute injection of PTZ (60 mg/kg) induced seizure in mice, while pretreatment with D-limonene inhibited PTZ-induced seizure. Repeated administration of PTZ (30 mg/kg) increased the seizure score gradually in mice, which was reduced in D-limonene (10 mg/kg)-pretreated group. In addition, D-limonene treatment increased glutamate decarboxylase-67 (GAD-67) expression in the hippocampus. Axonal sprouting of hippocampal neurons after kindling was inhibited by D-limonene pretreatment. Moreover, D-limonene reduced the expression levels of Neuronal PAS Domain Protein 4 (Npas4)-induced by PTZ. Furthermore, the adenosine A2A antagonist {"type":"entrez-protein","attrs":{"text":"SCH58261","term_id":"1052882304","term_text":"SCH58261"}}SCH58261 and ZM241385 inhibited anticonvulsant activity and gamma-aminobutyric acid (GABA)ergic neurotransmission-induced by D-limonene. Conclusion: These results suggest that D-limonene exhibits anticonvulsant activity through modulation of adenosine A2A receptors on GABAergic neuronal function.